When Colts' brass questioned second-year wide receiver LaVon Brazill's maturity during the spring, Wayne was assigned to look over the youngster.
He's an old dog — especially in NFL years — but he's still learning new tricks.
This is the second straight offseason in which Wayne has been asked to learn a new offense. That's no simple task after spending his first 11 years in the league running the same scheme with Peyton Manning.
No matter what system he's in, Wayne continues to produce. And his teammates continue to look up to him.
It's a lofty perch and one he couldn't have imagined as a rookie entering the league in 2001.
"When I first got in, I just wanted to feel like I was part of the family," he said. "You don't look down 13 years later and expect yourself to still be playing. You're just hopeful that you can stay as healthy as you can for as long as you can and then go from there."
Wayne has appeared in every Colts game since 2002, and he enters tonight's contest with 996 career catches for 13,428 yards and 80 touchdowns.
He's never been a numbers guy. But 1,000 receptions would put him into an elite club.
"A thousand catches, that's not something I ever dreamed of," he said. "It's kind of a weird feeling. It feels kind of weird to talk about it. But I'm happy. I guess that just shows that I've been playing a long time."