CBS claimed eight trophies during the telecast, giving the network a leading 21 wins including those from last week's creative arts ceremony. PBS was second with 14 wins.
The show had its unexpected moments, including Corbin Bernsen uttering two expletives during the in memoriam tribute that included his late mother Jeanne Cooper of "The Young and the Restless."
The ladies of "The Talk" presented outstanding talk show informative and when Aisha Tyler opened the envelope she quickly realized it was the wrong one.
"Oh, this is interesting," she said. "This winner is not in this category."
The audience in the International Ballroom of the Beverly Hilton gasped at the error.
"There better be a cocktail waiting on my table," Tyler said before being handed the correct envelope from the wings.
Tyler then announced "The Dr. Oz Show" as the winner.
"I was having heart palpitations, real ones," Dr. Mehmet Oz said onstage.
In another surprise, Scott Clifton of "The Bold and the Beautiful" and Billy Miller of "The Young and the Restless" tied for supporting actor in a drama series.
"It's fantastic," Miller said about sharing. "I assumed it was Scott's. I didn't hear my name which is why I was trying to sit down when they were pulling me up."
Julie Marie Berman of "General Hospital" won supporting actress honors. She has since left the ABC soap.
Kristen Alderson of "General Hospital" won the younger actress category.
In an upset, first-time nominee "CBS Sunday Morning" beat out heavyweights "Good Morning America" and the "Today Show" for outstanding morning program.
"We snuck in while nobody was looking," host Charles Osgood said.