Elwood did everything right to start the second set, bursting out to a 9-0 lead before the Titans called timeout.
Taylor battled back to 11-3 before Leisure started a 13-0 run on her serve to put the Panthers in firm control of the match.
The momentum carried into the third set, with Elwood scoring the first seven points before the Titans made their final run.
Taylor pulled as close as 12-6, but Tenasha Stevens served eight straight Panthers points to all but put the match away.
Stephens and Noone led the Panthers with seven kills each. Leisure and Kelsey Hughes added four kills apiece, and Holly Short and McKenzie Wilson finished with three kills and two blocks each. Short also had a pair of aces.
Elwood will meet Madison-Grant in the first semifinal Saturday at 11 a.m. The second semifinal will pit the winners of Thursday's matches between Tipton and Eastern at 6 p.m. and fifth-ranked Alexandria and Sheridan around 8 p.m.
The Panthers' familiarity with the Argylls (23-9) could be a bonus. They know where Madison-Grant star Jessica Hull likes to hit and how she'll likely attack their defense.
But the Argylls, of course, have just as much info on Elwood.
"We know what they've got," Short said. "Now it's up to us in practice to get ready for that."