Common Joint Pain Therapy Could Be Harmful, Says Study. Conducted by researchers at the Boston University of Medicine, the report was published in the journal, 'Radiology.'. It found that corticosteroid injections administered in the knees and hips could actually speed up osteoarthritis. Long-term effects could also speed up the need for joint replacement surgeries. The intra-articular corticosteroid injections in the hips and knees are not as safe as we thought, Ali Guermazi, Lead Study Author, via NBC News. The injections are intended to reduce inflammation and pain. According to the study, 8 percent of the 459 patients who received one to three injections of the therapy developed complications. Osteoarthritis is a chronic condition affecting 30 million Americans. Doctors recommend noninvasive treatments such as exercise, weight loss and physical therapy before trying injections